High-Energy Mill

Quadro Engineering’s H20 Comil high-energy mill is the next generation of conical milling for API, fine chemical, and cosmetic powder processing. It is designed to meet high yield efficiencies and the narrow particle size distribution demands of API, fine chemical, and cosmetic powder processing facilities worldwide. The H20 offers best-in-class, cGMP, high-containment sanitary features, RPM adjustable capabilities, and a portable, high-quality equipment design.

Product containment and minimization of operator exposure to fine chemicals, APIs, and cosmetic powders are of increasing importance. However, achieving these levels can be expensive, given the additional equipment required. The H20 high-energy Comil is designed to fully contain all products in the processing and receiving sections of the machine to 1 µg/cu m levels, enabling pharmaceutical processors to achieve desired containment levels with minimal additional capital investment. Containment features include safety-interlocked impeller purged seal, a tightly sealed mill housing, and optional wash-in-place (WIP) capabilities. The H20 Comil is available in an XP Version and with ATEX certification.

The H20 Comil offers advantages in particle size distribution milling control for d97 targets in the 250-400µm range (typically 30–70% more size reduction than traditional conical mills). The design of the mill housing with optional independently controlled feeder, enhances powder incorporation rate adjustability, resulting in very narrowly focused powder distribution curve spans to reduce out-of-spec product waste. The H20 provides a wide RPM milling range to accurately shift target particle distributions up or down, particularly important when milling multiple powders with varying characteristics. Additionally, the H20 offers a wide range of screens and impellers, enabling greater milling control and product quality.

An important benefit of the H20 Comil technology is the ability to provide higher percentage yield efficiencies for most production applications when compared to traditional mills in the sub-400µm d97 target range. This high rate of product recovery greatly reduces associated costs from product waste, and time spent in report preparation when notifying governing bodies of excess API losses.  

Quadro Engineering, Waterloo, ON, Canada 519-884-9660 www.quadrocomil.com

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